The Berlin Charité hospital in the 1880s, on the cusp of becoming the most famous in the world. A young admitted patient turned nurse-in-training moves through wards where Koch, Behring, and Ehrlich are making the discoveries that will define modern medicine. ARD's lavish period series weaves medical breakthroughs into the daily tension of a hospital that saves and fails lives by the hour, and returns in later seasons to revisit the same walls through the world wars and the Berlin Republic.